[UPDATED 2021] NABP FPGEE Questions Prepare with Free Demo of PDF [Q149-Q171]

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[UPDATED 2021] NABP FPGEE Questions Prepare with Free Demo of PDF

NEW 2021 Certification Sample Questions FPGEE Dumps & Practice Exam


NABP FPGEE Exam Syllabus Topics:

TopicDetails
Topic 1
  • Utilize pharmacokinetics to calculate, evaluate, and individualize drug therapy
  • Fundamental pharmacophores for drugs used to treat diseases
Topic 2
  • Marketing of goods and services: product versus service pricing, distribution, promotion
  • Structure-activity relationships in relation to drug-target interactions
Topic 3
  • Social and Behavioral Aspects of Pharmacy Practice
  • Patient adherence to therapies and recommendations
Topic 4
  • Interpret clinical pharmacokinetics of commonly used and low-therapeutic-index drugs
  • Materials and methods used in preparation of drug forms
Topic 5
  • Function of the major body systems and homeostatic impact at organ and system level
  • Pharmacodynamics of drug binding and response
Topic 6
  • Utilize pharmacogenomics to calculate, evaluate, and individualize drug therapy
  • Classes of pharmacologically active natural products
Topic 7
  • Role of automation and technology: pharmacy informatics, information management
  • Health care delivery financing in the United States
Topic 8
  • Planning, including delineation between business and strategic planning
  • Concepts of crude drugs, semi-purified, and purified natural products
Topic 9
  • General microeconomic and general macroeconomic principles
  • Mechanisms of action of drugs of various categories including biologics
Topic 10
  • Physicochemical properties relating to drug entities and dosage forms
  • Principles of bioavailability and bioequivalence

 

NEW QUESTION 149
Side effect of nedocromil is:

  • A. Dysphonia
  • B. Nausea
  • C. Thiocyanate poisoning
  • D. Neuromuscular paralysis
  • E. Growth retardation in children

Answer: B

 

NEW QUESTION 150
Mechanism of action of doxorubicin is:

  • A. Allosterically enhances GABAergic inhibition
  • B. alpha antagonist
  • C. Inhibits peptidyl transferase
  • D. beta antagonist
  • E. Inhibits topoisomerase II

Answer: E

 

NEW QUESTION 151
Example of fourth generation cephalosporin includes:

  • A. Cefoxitin
  • B. Ceftriaxone
  • C. Cefipime
  • D. Cefixime
  • E. Cefotaxime

Answer: C

 

NEW QUESTION 152
Mechanism of action of FK506 is:

  • A. Inhibits calcineurin
  • B. Inhibits phospholipid synthesis
  • C. Reduces calcium influx into neurons
  • D. Induces DNA damage under anaerobic conditions
  • E. Inhibits phospholipase C

Answer: A

 

NEW QUESTION 153
A patients with allergy to Sulphonamides (i.e.: SulphametoxazolE. can take all of the following
medications, EXCEPT:

  • A. Celecoxib
  • B. Tetracycline
  • C. Clindamycin
  • D. Penicillin
  • E. Lidocaine

Answer: A

 

NEW QUESTION 154
Class of phenobarbital is:

  • A. Barbiturates
  • B. Antiprotozoan agents
  • C. Antimycobacterial
  • D. Sedatives
  • E. Benzodiazepines

Answer: B

 

NEW QUESTION 155
Indication of doxycycline is:

  • A. Bacteroides (other than Bacteroides fragilis)
  • B. Water intoxication
  • C. Asthma
  • D. Meniere's disease
  • E. Broad spectrum antibacterial agent

Answer: E

 

NEW QUESTION 156
Diazepam Injection U.S.P
Diazepam 5 mg/ml
Ethanol 10%
Propylene glycol 40%
Benzyl alcohol 1.5%
Water for Injection qs 100%
In the formulation given above, the following ingredient(s) function(s) as a cosolvent(s):
I ethanol
II propylene glycol
III benzyl alcohol

  • A. I, II and III
  • B. III only
  • C. I only
  • D. I and II only
  • E. II and III only

Answer: D

 

NEW QUESTION 157
Atropine is the primary example of an important class of muscarinic antagonists which are esters of tropic
acid and which contain:

  • A. aniline and piperidine rings.
  • B. pyrrolidine and piperidine rings.
  • C. pyrrolidine and piperazine rings.
  • D. aniline and pyrrolidine rings.
  • E. aniline and piperazine rings.

Answer: B

 

NEW QUESTION 158
Mechanism of resistance of dicloxacillin is:

  • A. Mutations in M (matrix) protein
  • B. Beta-lactamase
  • C. Decreased drug uptake by bacteria
  • D. Penicillin binding proteins (PBPs)
  • E. Antibodies resulting from streptococcal infection

Answer: D

 

NEW QUESTION 159
Uricosuric agents are used in gout treatment by inhibiting the uric acid re-absorption in the proximal
tubules, the best example of a uricosuric agent is:

  • A. sulphinpyrazone
  • B. Indomethacin
  • C. Methotrexate
  • D. Penicillamine
  • E. Allopurinol

Answer: A

 

NEW QUESTION 160
Characteristics of GOUT, a group of disorders of purine and pyrimidine metabolism may include:
I- Hereditary metabolite disease marked by inflammation of the joints
II- The joint inflammation is caused by precipitation of uric acid crystals
III- It is a type osteoporosis

  • A. III only
  • B. All are correct
  • C. I only
  • D. I and II only
  • E. II and III only

Answer: D

 

NEW QUESTION 161
Intra-articular means:

  • A. In the spinal fluid
  • B. In the joint space
  • C. In the tissues space
  • D. In the dermis
  • E. In the spinal column

Answer: B

 

NEW QUESTION 162
Correct statements regarding aminoglycosides may include:
I- Has a half-life of 12hours
II- The effect continue remain after all drug is eliminated
III- The relation plasma concentration and half-life is not clear

  • A. III only
  • B. All are correct
  • C. II and III only
  • D. I only
  • E. I and II only

Answer: C

 

NEW QUESTION 163
Condition characterized by a reversible form of airflow obstruction is known as:

  • A. Cirrhose
  • B. Embolism
  • C. Jaundice
  • D. Aneurism
  • E. Emphesema

Answer: E

 

NEW QUESTION 164
Colchicine is used as anti-inflammatory agent in the acute treatment of:

  • A. Osteoporosis
  • B. Rheumatoid arthritis
  • C. Osteomyelites
  • D. Pressure atrophy
  • E. Gout

Answer: E

 

NEW QUESTION 165
Prednisone may produce all of the following effects, EXCEPT:

  • A. hypoglycemia
  • B. sodium retention
  • C. peptic ulceration
  • D. lowered resistance to infection
  • E. skeletal muscle weakness

Answer: A

 

NEW QUESTION 166
Mechanism of action of vincristine is:

  • A. Reduces peripheral insulin resistance
  • B. Mitotic spindle poison
  • C. Increases peripheral tissues sensitivity to insulin
  • D. Inhibits Na-K-2Cl transporter
  • E. Inhibits organification of iodine by thyroid gland

Answer: B

 

NEW QUESTION 167
Which of the following agents would be used in the treatment of infections caused by Helicobacter pylori
as combination therapy?

  • A. Clarithromycin, azithromycin and lansoprazole
  • B. Penicillin, amoxicillin, ampicillin and metronidazole
  • C. Ceftriaxone and metronidazole only
  • D. Combinations of antibiotic should not be used due to resistance.
  • E. Clarithromycin, amoxicillin, omeprazole and metronidazole

Answer: E

 

NEW QUESTION 168
Dopamine is useful in the treatment of cardiogenic shock because it:
I selectively dilates renal and mesenteric vascular beds.
II does not induce peripheral vasoconstriction.
III decreases the force of myocardial contraction.

  • A. I, II and III
  • B. III only
  • C. I only
  • D. I and II only
  • E. II and III only

Answer: C

 

NEW QUESTION 169
Which pyrimidine base is not present in RNA sequence?

  • A. Uracil
  • B. Adenine
  • C. Thiamine
  • D. Guanine
  • E. Cytosine

Answer: A

 

NEW QUESTION 170
All are correct concerning the action of corticosteroids in asthma status, EXCEPT:

  • A. Decrease production of inflammatory mediators
  • B. Increase -agonist receptors response
  • C. Relieve brochocontriction
  • D. Suppress the inflammatory response
  • E. Decrease airway responsiveness to inflammation

Answer: C

 

NEW QUESTION 171
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