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A00-282
  • Exam Code: A00-282
  • Exam Name: Clinical Trials Programming Using SAS 9.4
  • Updated: Aug 19, 2026
  • No. of Questions: 144 Questions and Answers
  • Download Limit: Unlimited
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SASInstitute A00-282 Exam Syllabus Topics:

SectionObjectives
Topic 1: SAS Programming for Clinical Trials- Reporting and Analysis
  • 1. Statistical reporting with SAS procedures
    • 2. Listings, tables, and figures generation
      - Data Management
      • 1. Dataset merging and manipulation
        • 2. Data cleaning and transformation
          Topic 2: Clinical Trials Data Standards- CDISC Standards
          • 1. SDTM structure and implementation
            • 2. ADaM datasets and analysis-ready data
              Topic 3: Regulatory and Clinical Research Concepts- Clinical trial workflow
              • 1. Regulatory submission basics
                • 2. Study design fundamentals

                  SASInstitute Clinical Trials Programming Using SAS 9.4 Sample Questions:

                  1. You have been asked to import an Excel spreadsheet.
                  What will lead to substantial differences between the original Excel spreadsheet and the resulting SAS data set?

                  A) the number of columns to be read from the Excel file
                  B) the number of rows to be read from the Excel file
                  C) multiple value types within a single row
                  D) multiple value types within a single column


                  2. You want to calculate the p-value of Fisher's exact test for a 3x3 table.
                  Which option must you add to the TABLES statement of PROC FREQ?

                  A) EXPECTED
                  B) CHISQ
                  C) CMH
                  D) EXACT


                  3. What is the main focus of Good Clinical Practices (GCP)?

                  A) standard monitoring practices
                  B) protection of subjects
                  C) harmonized data collection
                  D) standard analysis practices


                  4. Which CDISC filename contains these items?
                  - Variable attributes
                  - Controlled terminology
                  - Computational methods

                  A) specs.xml
                  B) define.xml
                  C) SDTMIG.pdf
                  D) acrf.pdf


                  5. In a Statistical Analysis Plan (SAP) the following statement is written:
                  To test the association between the pain intensity reported by the patient and the treatment the patient has been administered, a Cochran-Mantel-Haenszel test will be performed adjusting for the country of the patient's investigational site.
                  The following variables and levels are used:
                  - Pain intensity (PAIN): "No pain", "Mild pain", "Moderate pain", "Severe pain", "Most severe pain"
                  - Treatment group (TREAT): "Placebo", "Drug A", "Drug B"
                  - Country (COUNTRY): Eight different values.
                  The following program is written to perform this analysis:
                  proc freq data=pain;
                  by COUNTRY;
                  tables PAIN * TREAT / cmh;
                  run;
                  This code does not produce the analysis requested by the SAP.
                  What is wrong with this code?

                  A) The option CMH should be on the PROC FREQ statement instead of on the TABLES statement.
                  B) The variable PAIN should be on the BY statement along with the variable COUNTRY.
                  C) The variable COUNTRY should be on the TABLES statement instead of the BY statement.
                  D) The variables PAIN and TREAT should be on the BY statement, and the variable COUNTRY should be on the TABLES statement.


                  Solutions:

                  Question # 1
                  Answer: D
                  Question # 2
                  Answer: D
                  Question # 3
                  Answer: B
                  Question # 4
                  Answer: B
                  Question # 5
                  Answer: C

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