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BPS Pharmacotherapy (Part1 and Part2) Sample Questions:

1. A 59-year-old man presents to the neurology clinic with recently diagnosed Parkinson's disease.
At his last visit 2 months ago, selegiline therapy was instituted, and he is tolerating it well. The patient still complains of tremor and rigidity that are interfering with both professional and leisure activities. Which option is most appropriate at this time?

A) Change to amantadine.
B) Change to entacapone.
C) Change to carbidopa/levodopa.
D) Change to ropinirole.

2. A physician suspects that a patient's symptoms are related to abrupt discontinuation of a certain drug and asks the pharmacotherapy specialist about common reactions in this type of situation.
A literature search produces one case report of a discontinuation syndrome involving the drug.
What is the most appropriate action to take with regard to the current suspected adverse event?

A) Report the event to the FDA MedWatch program.
B) Report the event to the P & T Committee.
C) Complete a manufacturer's adverse event report.
D) Write and submit a case report detailing the event.

3. Investigators studying the relative nephrotoxicity of two aminoglycosides selected their sample size to detect a reduction in toxicity of 10%. Which of the following is the power of this study if the probability of falsely rejecting the null hypothesis is 0.05 and the probability of falsely accepting the null hypothesis is 0.20?

A) 0.80
B) 0.10
C) 0.05
D) 0.95

4. A 60-year-old patient has a 15-year history of type 2 diabetes mellitus, hypertension, and dyslipidemia. The patient, who denies smoking or drinking, complains of early satiety, a full feeling, bloating, and vomiting, for the past 2 months. Current medications include glipizide, metformin, and atorvastatin. The most recent A1C was 9.8%. Liver and renal function test results are within normal limits.
Which of the following would be most appropriate for managing these complaints?

A) Start metoclopramide.
B) Begin intravenous fluids.
C) Discontinue metformin.
D) Start simethicone.

5. A hospital requests a policy and procedure document for the monitoring and reporting of significant adverse drug reactions. Which agency requires a policy for the reporting of adverse drug reactions by hospitals?

A) Institute for Safe medication Practices
B) Joint Commission
C) Food and Drug Administration
D) National Committee for Quality Assurance

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